Syllabus (Fourth Edition, 2023)
Physiology of Haematological System
Pharmacology of Haematological System
Measurement of Haematological System
Blood and Blood Products
Pharmacopeia: Haematological
Physiology of Haematological System
i. Outline the physiological production of blood and its constituents.
ii. Explain the major blood groups and the principles of cross matching.
iii. Outline the constituents and functions of plasma.
iv. Describe the process and regulation of haemostasis, coagulation, and fibrinolysis.
v. Describe the mechanisms of preventing thrombosis including endothelial factors and natural anticoagulants.
vi. Explain the physiological consequences of acute and chronic anaemia.
Pharmacology of Haematological System
i. Understand the pharmacology of anti-coagulants, anti-platelet drugs, thrombolytic drugs, and anti-fibrinolytic drugs.
Measurement of Haematological System
i. Outline the methods for assessing coagulation (including TEG and ROTEM).
ii. Outline the methods for assessing platelet function and fibrinolysis.
Blood and Blood Products
i. Understand the pharmacology of blood and its components, including individual factor replacement.
ii. Understand the adverse consequences of blood transfusion, including that of massive blood transfusion and storage lesions.
iii. Understand the process of collection and production of blood and its components.
Pharmacopeia: Haematological
| LEVEL 1 | LEVEL 2 | LEVEL 3 |
|---|---|---|
| Anticoagulants | Anticoagulant Reversal Agents | |
| Low molecular weight heparin (LMWH) | Apixaban | Idarucizumab |
| Unfractionated Heparin (UFH) | Bivalirudin | Protamine |
| Warfarin | Dabigatran | Vitamin K |
| Rivaroxaban | ||
| Anti-platelet drugs | ||
| Aspirin | ADP receptor blockers | |
| Clopidogrel | ||
| Ticagrelor | ||
| Prasugrel | ||
| GPIIb/IIIa inhibitors | ||
| Abciximab | ||
| Tirofiban | ||
| Blood Products | Fibrinolytics | |
| Cryoprecipitate | Alteplase | |
| Fresh Frozen plasma | Tenecteplase | |
| Platelets | Antifibrinolytics | |
| Red blood cells | Tranexamic acid | |
| Fractionated plasma products | ||
| Albumin | Fibrinogen concentrate | Antithrombin III |
| Prothrombinex | Factor IX | |
| Factor VIIa | ||
| Factor VIII | ||
| Intravenous Immunoglobulin | ||
SAQs
VIVAs
| 2023B | Blood type, grouping Strucure of platelet, haemostasis |
| 2023A | Packed Red blood cells preparation |
| 2022B | Red cell production, storage and transfusion Viscoelastic assay, parts of curve |
| 2022A | Viscoelastic haemostatic assays (TEG, ROTEM) |
| 2021B | Formation of RBC Thromboelastography Coagulation, viscoelastic haemostatic assays (TEG, ROTEM) |
| 2021A | Viscoelastic measurement of coagulation, information obtained. Anti-platelet pharmacology Blood groups and determination |
| 2020B | Classic intrinsic pathway, coagulation Cell-based model, initial phase of coagulation Platelet production, anti-platelet drugs |
| 2019B | Coagulation after tissue trauma, arterial pressure |
| 2019A | |
| 2018B | Thromboelastography, label the trace |
| 2018A | The pharmacology of common anticoagulants (UFH) and the physics of arterial lines. Outline the different blood groups and explain why they are different. |
| 2017B | ABO, blood transfusion, CNS physiology and pharmacology Coagulation and lab assessment. Injury to vessel wall that lead to formation of a haemostatic plug |
| 2017A | knowledge of blood groups and coagulation |
| 2016B | |
| 2016A | |
| 2015B | |
| 2015A | physiology and pharmacology of iron and haemoglobin |
| 2014B | |
| 2014A | |
| 2013B | |
| 2013A | |
| 2012B | blood products and transfusion, storage, TXA |
| 2012A | Components of blood, Blood groups, antigens, changes to blood stored over time, process of group and screen |
| 2011B | |
| 2011A | |
| 2010B | Coagulation cascade, Heparin pharm |
| 2010A | |
| 2009B | |
| 2009A | Red Blood Cells and the Clark electrode |
| 2008B | |
| 2008A | |
| 2007B | Heparin as Prophylaxis against DVT after Acute Stroke – data table |
Recent Comments