Syllabus · Historical · V4 (2023) · Nervous System – Including Pain

K1 · Nervous System Physiology

K1.iii · Nervous System Physiology

Official V4 objective
Describe the anatomy and regulation of cerebral circulation.
2 SAQ topics 11 SAQ appearances 17 VIVA stations

Written examination

SAQ history

11 appearances
(a) List the normal parameters for cerebral blood flow (5% of marks). (b) Describe the physiological factors that influence cerebral blood flow (95% of marks).
62%
Describe the physiological factors that influence cerebral blood flow?
56%
Outline the physiological factors that influence cerebral blood flow.
19%
Using a diagram, explain the effect of PaO2, PaCO2 and MAP (Mean Arterial Pressure) on cerebral blood flow (CBF). (60 % of marks) Outline the effects of propofol and ketamine on CBF and cerebral metabolic requirement for oxygen (CMRO2). (40% of marks)
74%
Using a diagram, explain the effect of PaO2, PaCO2 and MAP (mean arterial pressure) on cerebral blood flow (60% marks). Outline the effects of propofol and ketamine on cerebral blood flow (CBF), cerebral metabolic requirement for oxygen (CMRO2), and cerebral venous oxygen saturation (40% marks).
44%
Describe the control of cerebral blood flow.
50%
Outline the physiological factors that influence cerebral blood flow.
33%
With respect to the blood brain barrier (BBB), outline the following: (a) the structure (15% of marks). (b) its function (25% of marks). (c) the mechanisms by which substances, including drugs move across the BBB and explain how this is determined or regulated (45% of marks). (d) the regions that lie outside the BBB and their purpose (15% of marks).
24%
Describe the structure and function of the blood brain barrier
33%
Describe the blood brain barrier (50% of marks). What characteristics does a drug need to effectively penetrate the blood brain barrier? (50% of marks)
41%
Describe the blood brain barrier. (50% of marks) What characteristics does a drug need to effectively penetrate into the central nervous system? (50% of marks)
22%

Oral examination

VIVA history

17 stations

Sources: objective text from the relevant CICM syllabus; historical SAQ and VIVA wording from CICM examiner reports.