O2.iv · Gastrointestinal Pharmacology

This viva tested knowledge of Respiratory Physiology. It discussed compliance, Functional Residual Capacity (FRC), Pressure Volume Loops and the work of breathing. It went on to discuss abdominal pressure, splanchnic blood flow and pharmacology of terlipressin.

The initial information given to the candidates was - This station is mostly concerned with the pharmacology of drugs acting on the gastrointestinal tract. What is a prokinetic? This viva explored the candidates’ knowledge in relation to the following points Prokinetics, examples of prokinetics, mechanism of action, general pharmacology of metoclopramide GIT secretions Laxatives, mechanism of action of lactulose Octreotide, mechanism of action, general pharmacology, indications for use Examination feedback: This is an important, and potentially overlooked, area of clinical ICU practice. Candidates breadth and depth of knowledge for this important topic was lower than expected. In particular was mechanism of action of prokinetics, laxatives (of which most of the discussion centred around lactulose) and octreotide.