D.iv · Variability in Drug Response

Official V4 objective

Describe variability in drug responses due to critical illness.

Written examination

SAQ history

2 appearances

2 exam appearances

2022A Q01

Outline the effects of critical illness on drug pharmacokinetics, including examples.

47%

2013A Q13

Outline the effects of critical illness on drug pharmacokinetics. Give examples.

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Oral examination

1 station

2026A · VIVA 8
Relevant examiner prompt

In critical illness we risk underdosing meropenem. Explain what patient and drug factors lead to this.

71.2% successful

Sources: objective text from the relevant CICM syllabus; historical SAQ and VIVA wording from CICM examiner reports.