Syllabus · Current · V5 (2025) · Haematological and Immunological System
N2 · Physiology of Immunological System
N2.ii · Innate & Adaptive Immunity
Outline innate and acquired immunity including how these systems interact in the immune response.
Written examination
SAQ history
Immunity — B/T Lymphocytes
1 exam appearance
Immunity — Complement
2 exam appearances
Describe the complement system using the following headings: (a) components (30% of marks) (b) activation pathways (10% of marks) (c) role and functions (50% of marks) (d) control and regulation (10% of marks)
54%
Describe the components and function of the complement system including the role, activation and control?
8%
Immunity — Host Defence
1 exam appearance
Immunity — Immunisation
1 exam appearance
Immunity — Innate Immunity
2 exam appearances
(a) Define innate immunity including how it differs from adaptive immunity (10% of marks). (b) Outline the components of the innate immune system including their role in the immune response (90% of marks).
59%
(a) Define innate immunity including how it differs from adaptive immunity (10% of marks). (b) Outline the components of the innate immune system including their role in the immune response (90% of marks).
17%
Oral examination
VIVA history
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2025B · VIVA 8
This viva will examine immunology and haematology. How does the body defend itself against pathogens?
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2022A · Day 1 · VIVA 4
This viva will explore your understanding of the immune system. What are the key features and possible benefits of innate immunity?
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2017B · Day 1 · VIVA 8
This viva will test your knowledge of immunology and associated pharmacology. What is innate immunity?
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2011B · VIVA 2
This Viva will examine elements of the acute inflammatory response and serotonin physiology and pharmacology. Q 1. Describe the mechanism of the acute inflammatory response to tissue injury. Subsequent questions explored knowledge of what cytokines are, and what major roles they play in the body, the complement system, apoptosis, immune basis of rejection of allogeneic organs, and serotonin.
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2009A · VIVA 2
This viva will test your knowledge of the physiology and pharmacology of the Immune System. Outline the body’s defence mechanisms against infection.
Sources: objective text from the relevant CICM syllabus; historical SAQ and VIVA wording from CICM examiner reports.