Core pharmacology

Class Group

Antiviral

Legacy Cicm Level

Level 3

Introduction

Oseltamivir and Zanamivir

Mechanism of action

inhibit neurominidase resulting in impaired viral release from infected cells. Neurominidase cleaves the sialic acid on the cell membrane allowing viral budding.

Adverse Effects Toxicity

1. Psychiatric symptoms
2. N/V/D
3. Bronchospasm