Core pharmacology

Legacy Cicm Level

Level 3

Main Action

Oxidative damage.

Mechanism of action

1. Sporicidal
2. Cheap
3. Broad spectrum
Most effective for intact skin

Antimicrobial Spectrum

Onset: Iodine is bacteriocidal in 1 minute and kills spores in 15 minutes. However in povidine compounding it has a delayed onset

Duration:
No sustained effect

Resistance Mechanism

- Bacteria (G+ve and –ve and acid fast)
- Sporicidal
- Viruses
- Fungi

Ineffective Against

Prions
Hydrophilic viruses

Route And Dose

1. Hypersensitivity reactions
2. Delayed onset without residual activity
3. Stains clothes and dressings