Pharmacopeia

CWP-0010

ALCOHOL

Anti-infectives · Anti-infectives · Level 3

Core pharmacology

Legacy Cicm Level

Level 3

Main Action

Likely act by denaturing proteins

Mechanism of action

Evaporative effects are useful when sinks with running water are not available

Antimicrobial Spectrum

Onset: Rapid

Duration:
Lack residual action because they evaporate completely

Resistance Mechanism

- Gram positives and negatives
- Acid fast bacteria are susceptible
- Lipophilic viruses may be susceptible
- Many fungi

Ineffective Against

Spores and prions
Hydrophilic viruses are less susceptible

Special Points

Optimal bacteriocidal concentration is 60-90%

Route And Dose

1. Flammable- must be allowed to dry fully before diathermy or laser surgery
2. Corneal damage
3. Skin drying
4. Ineffective against C. Dif spores