Core pharmacology

Class Group

Antiplatelet

Legacy Cicm Level

Level 3

Introduction

GP IIb/IIIA Inhibitor

Main Action

Platelet inhibition

Mechanism of action

Similar mechanism as tirofiban but monoclonal
antibody

Adverse Effects Toxicity

Haemorrhage, thrombocytopenia, human antichimeric antibody development, allergic reaction

Metabolism

Platelet function
typically returns to
normal 24-48 hours after
infusion ceases

Excretion

Platelet function
typically returns to
normal 24-48 hours after
infusion ceases