Antifungals — Fluconazole & Amphotericin

Fluconazole, amphotericin and caspofungin are anti-fungal drugs. (a) For each drug listed above, outline the following: (i) the class (15% of marks). (ii) the mechanism of action (45% of marks). (iii) TWO microbes against which they are active (30% of marks). (marks in each section are equally distributed between the 3 drugs listed) (b) List TWO serious side effects seen with ANY anti-fungal drug, include the agent most associated with each effect listed in your answer (10% of marks).