Syllabus · Current · V5 (2025) · Nervous System including autonomic and pain

H2 · Nervous System Physiology

H2.vii · Neurotransmitters

Official V5 objective
Classify and outline the major endogenous neurotransmitters of the nervous system including their role, receptor(s) and distribution.
2 SAQ topics 2 SAQ appearances 4 VIVA stations

Written examination

SAQ history

2 appearances
Classify the 5HT receptors and give examples of pharmacological agents that affect them (60% of marks). Outline the pharmacology of ondansetron (40% of marks).
45.4%
For each neurotransmitter listed below: a) acetylcholine (ACh), b) gamma-aminobutyric acid (GABA), c) noradrenaline (NorAd), d) serotonin (5-HT). Outline the following: i) target receptors, including type and location (15% of marks per neurotransmitter), Downstream receptor mechanisms NOT required. ii) functional role(s) (10% of marks per neurotransmitter).
38.6%

Oral examination

VIVA history

4 stations

Sources: objective text from the relevant CICM syllabus; historical SAQ and VIVA wording from CICM examiner reports.