Opioid Receptor Signalling, Analgesia & Adverse Effects

Current · V5 (2025) → H4.ii 1 exam appearance

2025A Q19

Exam question

(a) Describe the intracellular events that occur following opioid receptor activation (25% of marks). (b) Describe the locations where opioids produce analgesia and the mechanisms by which they exert these effects (45% of marks). (c) Outline the mechanism by which morphine causes the following side effects: (i) Respiratory depression (15% of marks). (ii) Constipation (15% of marks).

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Past papers

Exam appearances

1 appearance

Exam	Exact exam wording	Candidate success
2025A Q19	(a) Describe the intracellular events that occur following opioid receptor activation (25% of marks). (b) Describe the locations where opioids produce analgesia and the mechanisms by which they exert these effects (45% of marks). (c) Outline the mechanism by which morphine causes the following side effects: (i) Respiratory depression (15% of marks). (ii) Constipation (15% of marks).	43%